Master Biologie structurale, génomique - Biochimie structurale (BS)

[24-25]-M2-S1-NMR

[24-25]-M2-S1-Crystallography (ML Garron)

[24-25]-M2 BSG - Integrated Practical Projects in Structural Biology (E. Garcin; M. Martinho)

[24-25]-Seminars in Current Biochemistry

A set of seminars on current topics in Biochemistry.

[24-25]-Molecular Modeling & Drug Design

Dynamics of target and drugs (6 H CM) :
How to encompass the entropic part of protein - drugs interactions ?
Overview on thermodynamics (1:30)
Evaluation of Entropy; from score functions to molecular simulations (1:30)
Overview on Integrated path molecular simulations and integration of artificial intelligence (3h CM)

TD : 6 X 3 H (Jupiter notebooks, modelling programs, and Virtual reality -VR- handling)

TD n°1 Exploring molecular flexibility (Gromacs, jupyter notebooks, and VR)
TD n°2 Structural Analysis of Target Drug interactions (ChimeraX and VR)
TD n°3 IA for docking and drug evaluation (Alphafold, and other IA based Jupyter notebooks)
TD n°4 Structure Based Drug Design (Molecular Docking, MOE)
TD n°5 Structure Based Drug Design (Pharmacophore Filtering, MOE)
TD n°6 Seeing Structure Activity relationship (SeeSAR)